CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

Bupropion HCL

· ingredient bupropionOther antidepressants· BUPROPION HYDROCHLORIDE 100 mg/1; BUPROPION HYDROCHLORIDE 75 mg/1
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per EA
$0.10670
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per EA — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other bupropion products, cheapest acquisition cost first. Per EA — confirm strength/form equivalence before switching.

ProductNADAC / EAvs this
buPropion Hydrochloride XL$0.07895−$0.02780
bupropion hydrochloride SR$0.10837+$0.00170
Bupropion Hydrochloride (XL)$0.11542+$0.00870
Bupropion Hydrochloride (SR)$0.27757+$0.17090
BUPROPION HCl ER (XL)$7.60+$7.49

Medicare Part D coverage · CY2026

On 328 plan formularies · typical tier 2
Prior auth 0% · Step therapy 0% · Quantity limit 27% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.