CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

COSOPT

ddorzolamide hydrochloride timolol maleate· ingredient timololBeta blocking agents· DORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mL; DORZOLAMIDE HYDROCHLORIDE 22.3 mg/mL; TIMOLOL MALEATE 6.8 mg/mL
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per ML
$0.92983
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per ML — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other timolol products, cheapest acquisition cost first. Per ML — confirm strength/form equivalence before switching.

ProductNADAC / MLvs this
Timolol Maleate$0.75535−$0.17450
timolol maleate$0.79615−$0.13370
COSOPT PF$1.08+$0.14980
Timolol maleate$1.60+$0.67080
Brimonidine Tartrate/Timolol Maleate$2.38+$1.45
Timoptic in Ocudose$5.94+$5.01
TIMOLOL MALEATE$13.33+$12.40
Timolol GFS$13.33+$12.40

Medicare Part D coverage · CY2026

On 328 plan formularies · typical tier 2
Prior auth 0% · Step therapy 0% · Quantity limit 1% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.