Drugs · acquisition-cost intelligence
Allergy Relief
Diphenhydramine· ingredient diphenhydramineAntihistamines for topical use· DIPHENHYDRAMINE 50 mg/1; DIPHENHYDRAMINE HCL 50 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per EA
$0.06040
NADAC — pharmacy acquisition cost, not a retail/cash price
Acquisition-cost history
Weekly NADAC per EA — the trend nobody else shows. 7 weeks.
2025-12-172026-05-20
Same-ingredient options by acquisition cost
Other diphenhydramine products, cheapest acquisition cost first. Per EA — confirm strength/form equivalence before switching.
| Product | NADAC / EA | vs this |
|---|---|---|
| basic care nighttime sleep aid | $0.00798 | −$0.05240 |
| Adult Allergy Relief Dye Free | $0.01987 | −$0.04050 |
| Aller-Ben | $0.03745 | −$0.02300 |
| Benadryl Extra Strength Itch Cooling | $0.04757 | −$0.01280 |
| anti itch | $0.05810 | −$0.00230 |
| Allergy | $0.06040 | +$0.00000 |
| Advil PM | $0.12716 | +$0.06680 |
| diphenhydramine hydrochloride | $0.93723 | +$0.87680 |
Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.