CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

Memantine and Donepezil Hydrochlorides Extended-release

Memantine and Donepezil· ingredient donepezilAnticholinesterases· DONEPEZIL HYDROCHLORIDE 10 mg/1; MEMANTINE HYDROCHLORIDE 14 mg/1; DONEPEZIL HYDROCHLORIDE 10 mg/1; MEMANTINE HYDROCHLORIDE 21 mg/1; DONEPEZIL HYDROCHLORIDE 10 mg/1; MEMANTINE HYDROCHLORIDE 28 mg/1; DONEPEZIL HYDROCHLORIDE 10 mg/1; MEMANTINE HYDROCHLORIDE 7 mg/1
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per EA
$11.97
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per EA — the trend nobody else shows. 7 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other donepezil products, cheapest acquisition cost first. Per EA — confirm strength/form equivalence before switching.

ProductNADAC / EAvs this
Donepezil$0.04571−$11.93
Aricept$0.04761−$11.92
Donepezil hydrochloride$0.76174−$11.21

Medicare Part D coverage · CY2026

On 142 plan formularies · typical tier 3
Prior auth 28% · Step therapy 4% · Quantity limit 25% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.