CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

Methotrexate

METHOTREXATE SODIUM· ingredient methotrexateOther immunosuppressants· METHOTREXATE SODIUM 25 mg/mL
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per ML
$3.36
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per ML — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other methotrexate products, cheapest acquisition cost first. Per ML — confirm strength/form equivalence before switching.

ProductNADAC / MLvs this
Methotrexate$0.16406−$3.20
Methotrexate$1.23−$2.13
methotrexate$2.57−$0.79180
Rasuvo$482.29+$478.93

Medicare Part D coverage · CY2026

On 325 plan formularies · typical tier 2
Prior auth 34% · Step therapy 0% · Quantity limit 0% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.