CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

TOPIRAMATE

topiramate· ingredient topiramate· TOPIRAMATE 15 mg/1; TOPIRAMATE 25 mg/1; TOPIRAMATE 50 mg/1
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per EA
$0.30433
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per EA — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other topiramate products, cheapest acquisition cost first. Per EA — confirm strength/form equivalence before switching.

ProductNADAC / EAvs this
topiramate$0.04260−$0.26170
Topamax$0.05949−$0.24480
Eprontia$1.61+$1.30
Qsymia$3.21+$2.90
topiramate$5.66+$5.36
Trokendi XR$9.01+$8.70
Topiramate$22.71+$22.40

Medicare Part D coverage · CY2026

On 328 plan formularies · typical tier 2
Prior auth 8% · Step therapy 0% · Quantity limit 0% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.