CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

Estradiol

· ingredient estradiol· ESTRADIOL 1 mg/1; ESTRADIOL 2 mg/1; ESTRADIOL .5 mg/1
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per EA
$0.06599
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per EA — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other estradiol products, cheapest acquisition cost first. Per EA — confirm strength/form equivalence before switching.

ProductNADAC / EAvs this
Estradiol$0.06599+$0.00000
ESTRACE$0.38605+$0.32010
ABIGALE$0.69593+$0.62990
Mimvey$0.70126+$0.63530
DIVIGEL$1.47+$1.41
ELESTRIN$3.52+$3.46
DOTTI$7.65+$7.59
Bijuva$8.69+$8.62

Medicare Part D coverage · CY2026

On 328 plan formularies · typical tier 1
Prior auth 0% · Step therapy 0% · Quantity limit 1% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.