CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

DIVIGEL

estradiol· ingredient estradiol· ESTRADIOL 1.25 mg/1.25g; ESTRADIOL 1 mg/g; ESTRADIOL .25 mg/.25g; ESTRADIOL .5 mg/.5g
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per GM
$1.47
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per GM — the trend nobody else shows. 8 weeks.

2025-08-202026-05-20

Same-ingredient options by acquisition cost

Other estradiol products, cheapest acquisition cost first. Per GM — confirm strength/form equivalence before switching.

ProductNADAC / GMvs this
Estradiol$0.06599−$1.41
Estradiol$0.06599−$1.41
ESTRACE$0.38605−$1.09
ABIGALE$0.69593−$0.77820
Mimvey$0.70126−$0.77290
ELESTRIN$3.52+$2.05
DOTTI$7.65+$6.18
Bijuva$8.69+$7.22

Medicare Part D coverage · CY2026

On 80 plan formularies · typical tier 4
Prior auth 0% · Step therapy 0% · Quantity limit 3% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.