CAI
Clinical Asset Index
by VOS Supply Group
Drugs · acquisition-cost intelligence

Estradiol valerate

· ingredient estradiol· ESTRADIOL VALERATE 10 mg/mL; ESTRADIOL VALERATE 20 mg/mL; ESTRADIOL VALERATE 40 mg/mL
What this is. Acquisition-cost intelligence for pharmacy & clinic buyers — the historical trend, generic-equivalent costs, and Part D posture. NADAC is a pharmacy acquisition cost (the national average pharmacies pay), not a retail or cash price — for consumer cash prices use GoodRx/your plan.
Acquisition benchmark · NADAC per ML
$21.00
NADAC — pharmacy acquisition cost, not a retail/cash price

Acquisition-cost history

Weekly NADAC per ML — the trend nobody else shows. 6 weeks.

2025-12-172026-05-20

Same-ingredient options by acquisition cost

Other estradiol products, cheapest acquisition cost first. Per ML — confirm strength/form equivalence before switching.

ProductNADAC / MLvs this
Estradiol$0.06599−$20.94
Estradiol$0.06599−$20.94
ESTRACE$0.38605−$20.62
ABIGALE$0.69593−$20.31
Mimvey$0.70126−$20.30
DIVIGEL$1.47−$19.53
ELESTRIN$3.52−$17.48
DOTTI$7.65−$13.35

Medicare Part D coverage · CY2026

On 224 plan formularies · typical tier 4
Prior auth 0% · Step therapy 0% · Quantity limit 0% of formularies

Sources: CMS NADAC (pharmacy acquisition cost), FDA NDC + RxNorm (identity), RxClass (therapeutic class), CMS Medicare Part D formulary (coverage). Observed reference data for professional buyers — not a retail/cash price, not pricing or medical advice. Verify before purchasing or substituting.